BEAUTY STARTS


WITH AWARENESS

THE TOP
10 NASTIES

Exploring ingredients commonly associated with irritation, sensitivity, and concerns around the eye area.

Top 10 Nasties

A curated list of cosmetic ingredients ÈYES avoids in formulas designed for use around the delicate eye area.
  1. Argireline
  2. Benzalkonium Chloride (BAK)
  3. Formaldehyde & donors
  4. Fragrance
  5. Isopropyl Cloprostenate
  6. Parabens
  7. Phenoxyethanol
  8. Retinols / Retin A
  9. Salicylic Acid
  10. Tea Tree Oil

Scientific sources behind our “Top 10 Nasties” list for sensitive eyes

The sources listed on this page represent a non-exhaustive selection of studies examining the impact of specific cosmetic ingredients on eye sensitivity.

1. Ozgur O, Murariu D, Parsa AA, Parsa FD. Dry eye syndrome due to botulinum toxin
type-A injection: guideline for prevention. Hawaii J Med Pub Health 2012;71(5):120-1237.
2. Chen X, Liu Y, Kam WR, Sullivan AG, Sullivan DA. Toxicity of cosmetic preservatives
on human ocular surface and adnexal cells. Exp Eye Res 2018;59:193-205.
3. Sullivan DA, da Costa AX, Del Duca E, Doll T, Grupcheva CN, Lazreg S, Liu SH,
McGee SR, Murthy R, Narang P, Ng A, Nistico S, O’Dell L, Roos J, Shen J, Markoulli M. TFOS. Lifestyle: Impact of cosmetics on the ocular surface. Ocul Surf. 2023 Apr 13;29:77-130.
4. Wang J, Liu Y, Kam WR, Li Y, Sullivan DA. Toxicity of the cosmetic preservatives
parabens, phenoxyethanol and chlorphenesin on human meibomian gland epithelial cells. Exp Eye Res 2020; 196:108057.
5.https://www.cosmeticsandtoiletries.com/regulatory/claims/120476614.html
6. N Horv.th O, Letul. V, Ruzicka T, Herzinger T, Goldscheider I, von Braunmuül T.
Periocular discoloration after using a prostaglandin analog for eyelash enhancement: evaluation
with refl ectance confocal microscopy. J Cosmet Dermatol 2017;16(1):18-20.
7. Kam WR, Liu Y, Ding J, Sullivan DA. Do cyclosporine A, an IL-1 receptor antagonist,
uridine triphosphate, rebamipide or bimatoprost regulate human meibomian gland epithelial
cells? Invest Ophthalmol Vis Sci 2016;57:4287-4294.
8. Ding J, Kam WR, Dieckow J, Sullivan DA. The influence of 13-cis retinoic acid on
human meibomian gland epithelial cells. Invest Ophthalmol Vis Sci.
2013;54:4341-4350.
9. Chen D, Wang J, Sullivan DA, Kam WR, Liu Y. Effects of terpinen-4-ol on meibomian
gland epithelial cells in vitro. Cornea 2020;39:1541-1546.

What you apply around the eyes matters

WHAT GOES
NEAR THE EYES MATTERS

From preservatives to fragrance compounds, these are the ingredients most often discussed in conversations around ocular wellness, irritation, and eye conscious beauty.

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